Webinar Objectives: 

• Review Chronic Transfusion Therapy (CTT) for Sickle Cell Anemia (SCA)
• Present a prospective study of RBC genotyping of SCA patients and transfused units during CTT
• Clinical applications

Speaker: Marianne E. McPherson Yee, MD

Webinar Objectives: 

• Geneotyping to resolve e-like Antibodies

Speaker: Dr. Shaun Lawicki, MBBS

Webinar Objectives: 

• Describe basic RHD genetics & biochemistry
• Discuss the complexity in the determining RhD antigen status in individuals with a serologic weak D phenotype
• List current recommendations from the participants of the AABB/CAP 2015 working party

Speaker: Sue Johnson MSTM, MT(ASCP)SBB

Webinar Objectives: 

• Identify the genetic mechanism for the inheritance of the ABH blood group antigen, including the Bombay phenotype
• Differentiate the transferases and biochemical structures of the ABH antigens
• Evaluate the characteristics of and relationship between antigens and antibodies in the ABO system
• Identify lectin reagents that show ABO blood groups specifically
• Assess the effects of disease and age on production of ABO antigens and antibodies
• Classify the A and B antigens into subgroups, including serologic characteristics, number of antigen site and frequency in the population

Speaker: LeeAnn Walker, MEd, MT(ASCP)SBB

Webinar Objectives:

• Discuss the purpose of antibody detection testing and techniques.
• Examine reagents used in antibody detection and crossmatch including potentiators and reagent red blood cells.
• Compare antibody detection testing to crossmatch testing

Speaker: Tricia Sanders

Webinar Objectives: 

• Review the Rh proteins and Rh genes
• Review Rh terminology
• Illustrate the challenges of serologic Rh antigen typings and how molecular methods can help
• Discuss the AABB recommendations regarding use of RHD genotyping to resolve serologic weak D phenotype
• Use cases to illustrate how RHD genotyping can aid in determination of risk of alloimmunization
• Demonstrate how RH allele matching can be used to find compatible blood for a patient with an antibody to a high prevalence of RH antigen

Speaker: Margaret A. Keller, PhD.

Webinar Objectives: 

• Define solid phase technology
• Recall the steps for processing a capture Assay
• Interpret Capture results
• Identify the Capture products offered by Immucor

Webinar Objectives: 

• Identify the Capture Strips and Plates
• Define how these strips and plates are used in Capture testing

Webinar Objectives: 

• Identify Capture Reagents
• Define purpose of Capture Reagents

Webinar Objectives: 

• Background
• Methods to obtain access for CCP
• NYC & the Covid-19 Pandemic
• CUIMC CCP clinical trials
• Impact on transfusion service operations

Speaker: Joseph Schwartz 

Webinar Objectives: 

• Define and categorize transfusion reactions
• Describe clinical manifestations of specific transfusion reactions
• Discuss patient evaluation and management when transfusion reactions is suspected

Speaker: Margo R Rollins, MD 

Webinar Objectives: 

• Define Pretransfusion Testing
• Recognize the Pretransfusion Processing Steps
• Identify the Purpose of the Crossmatch Test
• Recognize Characteristics of Serologic and Computer Crossmatch Methoids

Webinar Objectives: 

• Define Direct Antiglobulin Tests (DATs)
• Recognize Applications of the DAT
• Identify Reagents used in the DAT
• Interpret DAT Results

Webinar Objectives: 

• Hospitals and Blood Donar systems
• Blood Banks and Blood Transfusion
• Patient testing in Blood Banks
• Safe Blood Transfusion
• Blood Collection

Webinar Objectives: 

• Importance and significance in continuing education initiatives within the blood banking community

Speaker: Jay Slayten MS, MT(ASCP)SBB

Webinar Objectives: 

• What is and Red Blood Cell (RBC) and What is its importance
• RBC Critical Functions
• RBC Lifecycle and Membrane Structure
• Antigens on Membrane Surface

Webinar Objectives: 

• Describe the functions of enzymes on red blood cells
• Compare enzyme treatment to chemical treatment
• Discuss the use of enzyme treated red blood cells in antibody detection and identification pathways

Speaker: Tricia Sanders 

Webinar Objectives: 

• Discuss and interpret interactive immunohematology case studies

Speaker: Monica Kalvelage

Webinar Objectives:

• PICHE vs HLA
• Long- and Short-term effects
• How PIRCHE enhances antibody diagnostics
• PIRCHE walk through

Speaker: Matthias Niemann

Webinar Objectives: 

• Podcast style presentation with PIRCHE experts analyzing new frontiers in epitope matching

Speaker: Martha Deconinck  Matthias Niemann  Timothy Boadi​

Webinar Objectives: 

• Review the scope of BeadChip PreciseType^@ testing
• Discuss published indications for RBC genotyping in patients
• Describe Northwestern Memorial Hospital approach
• Examine benefits of DNA phenotyping in subsequent workups
• Discuss questions and comments

Speaker: Glenn Ramsey

Webinar Objectives:

• Review RBC alloimmunization persistence despite advances in serologic testing
• Discuss limitations of serological testing
• PreciseType@ HEA RBC genetic  testing helps overcome these limitations
• Clinical applications
• Questions and Answers

Speaker: Cassandra Josephson

Webinar Objectives: 

• Describe the application of molecular testing in the hospital donor center and transfusion service
• Discuss the impact of molecular testing on serologic antibody identification workups through case studies
• List the benefits of leveraging software to simultaniously view serology and molecular testing

Speakers: Jessie Singer MT (ASCP)  Cassandra Josephson MD

Webinar Objectives: 

• Introduction to Blood Bank basics
• Discuss limitations of serologic phenotyping
• Description of RBC molecular typing and potential advantages over serologic typing
• Application of RBC molecular typing

Speaker: Ross M Fasano

Webinar Objectives: 

• Optimization of HLA antibody testing
• Rapid Optimized Single Antigen Bead (ROB) protocol for LABscreen (Human Immunology 2017)
• Enhanced ROB protocols for LIFECODES LSA
• Development of a novel, prozone-resistant Dual Antibody Rapid Test (DART) protocol for LABscreen (ASHI Quarterly 2017)

Speaker: Robert Liwski

Webinar Objectives: 

• Basis of Antibody testing
• ASHI scoring system
• Assay Classification
• Luminex summary

Speaker: Dr. Michael Gautreaux

Webinar Objectives

• Challenges with single antigen testing
• HLA Class I Structural Variants - "Denatured Antigens"
• Conclusions from in-house studies
• Best practices in single antigen testing

Speaker: Bryan Ray

Webinar Objectives: 

• Comparison of current HLA typing methods
• Different HLA NGS manufacturers
• Workflow estimates
• Explanation of clinical runs

Speakers: Masako Osada, Ph.D. & ReaAnna Neville CHT(ABHI) 

Webinar Objectives: 

• HLA DNA bilble
• NGS definition, key terms, and general workflow
• Databank submission

Speakers: Michael D. Gautreaux  Kelly J. Ingram  David F Kiger

Webinar Objectives: 

• Compare and contract kidney transplant (Ktx)  in the USA and India
• Testing performed at UCSF for KTx
• Protocol used at UCSF for KTx
• Testing Details
• Optimal protocol for KTx in India

Speaker: Rajalingam Raja Ph.D.

Webinar Objectives: 

• Hematopoietic Stem Cell transplantation
• Serological Typing
• HLA Allele assignment
• Alternate donor
• Stem Cell transplantation challenges in India

Speaker: Dr. Uma Kanga

Webinar Objectives: 

• History of HLA matching
• HLA matching benefits patient survival
•  How to distinguish immunogenic and nonimmunogenic HLA mismatches
• Problem for the Hyperimmunized patient

Speaker: Frans Claas 

Webinar Objectives: 

• The process of stem cell transplantation
• Chimerism definition, examples, and analysis

Speaker: Dr. Anil Handoo

Webinar Objectives: 

•  HLA Typing
• Antigen and Alleles
• Transplantation

Speaker: Dr. Deborah Sage

Webinar Objectives: 

• Decision process to advocate for NGS
• Lab Planning
• Test Validation
• Implementation into clinical practice
• Reporting out NGS data
• Areas where NGS can help an HLA lab in solid organ translantation

Speaker: Peter Jindra

Webinar Objectives: 

• MIC Overview
• Role of non HLA antibodies in renal transplant
• Pathogenesis
• Early Studies
• Significance of pre Tx MICA
• Significance of post Tx MICA
• Mechanism of antibody formation
• Our study

Speaker: Dr. Mohit Chowdhry

Webinar Objectives: 

• ImmuLINK function and capabilities
• Hamilton Regional Library medicine program
• CoLabs and ImmuLINK

Speaker: Sandra Fazari MLT, BSC, MBA 

Webinar Objectives: 

• ImmuLINK background
• ImmuLINK demonstration

Speaker: Giuffre Gianni 

Webinar Objectives: 

• B-cell epitope in Kidney transplantation
• T-cell epitope in Kidney transplantation

Speakers: Sebastiaan Heidt  Eric Spierings

Webinar Objectives: 

• ABO Blood group systems
• How does FDA impact ABO Blood groups
• History of blood transfusion
• Landsteiner's Law

Webinar Objectives: 

• Explain the formation of H, A, and B antigens and soluble substances
• Interpret ABO typing results including ABO discrepancy testing
• Discuss ABO antibodies including immunoglobulin classes and the importance of reverse testing

Speaker: Tricia Sanders

Webinar Objectives: 

• Discuss the testing methodologies used for antigen typing
• Differentiate between monoclonal and polyclonal antisera
• Explain the importance of phenotyping in antibody identification
• Describe common antigen typing protocols for multiply transfused patients

Speaker: Trica Sanders

Webinar Objectives

• Distinguish immune response into the action of T Cells and B Cells.
• Recognize the role of immunoglobulins and cells involved in primary and secondary immune response.
• Outline function and process of complement activation in transfusion medicine.
• Demonstrate genetic concepts of blood groups exploring pedigree analysis and population genetics.

Speaker: Jayanna Slayten MS, MT(ASCP)SBB