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Werfen Introduces NanoTYPE® HLA-11 Plus — First RUO HLA Typing Kit with Full-Gene Coverage for All 11 Classical HLA Genes

Werfen, a global leader in specialized diagnostics, announced the launch of NanoTYPE® HLA-11 Plus, a next-generation HLA typing assay offering true full-gene coverage — from 5′UTR to 3′UTR — across all 11 classical HLA genes. This new addition to Werfen’s transplant diagnostics portfolio reflects the company’s ongoing commitment to innovation in histocompatibility and immunogenetics.

Designed for seamless integration with Oxford Nanopore Technologies® (ONT) long-read sequencing platforms, NanoTYPE HLA-11 Plus enables uninterrupted phasing across entire HLA genes, minimizing genotyping ambiguities and maximizing confidence in your data. Optimized for use with ONT’s Rapid Barcoding Kit, the assay supports fast, efficient library preparation and high-throughput multiplexing.

Key Features:

  • Full-gene coverage across all 11 classical HLA loci, including intronic regions
  • Seamless phasing with long-read nanopore sequencing
  • Compatible with ONT’s MinIONTM Mk1B and Mk1D, GridIONTM, and PromethIONTM 2 Solo (P2 Solo) platforms
  • Software with transparent QC metrics: exon coverage, allele imbalance, noise tracker, N50 read length

With the increasing demand for high-resolution, fully phased HLA typing, NanoTYPE HLA-11 Plus empowers researchers to achieve unambiguous results—especially in highly polymorphic regions.

With growing interest in epitope-based matching between deceased donors and transplant recipients, the need for fully phased, high-resolution HLA typing has become increasingly critical. NanoTYPE HLA-11 Plus directly addresses this need, paving the way for more precise and confident matching strategies.

Currently available as Research Use Only (RUO), NanoTYPE HLA-11 Plus reflects Werfen’s ongoing commitment to advancing transplant diagnostics.

We invite you to explore how NanoTYPE HLA-11 Plus can elevate your research and support more confident matching strategies.

Werfen

3130 Gateway Drive, P.O. Box 5625, Norcross, GA 30091-5625

Call 855-466-8267